This is very interesting indeed, this time I'm definitely not going to doubt Jagex one bit. It was funny before the old nuke no believed that they could have stopped the bots for a relatively long period of time and people really did expect a quick turn around of a week for the clients to be updated.
Jacmob seems to be pretty confident about this statement, I doubt he would come out with something so strong if he didn't himself believe that this update would encompass the majority or all different botting platforms.
It took months for the developers to release the new clients, and if this update is any time soon then they were only released for a couple of weeks. I can't see many developers sticking around, seems like they are fighting a losing battle.