I personally think he's one of the strongest bruisers in the game.
The problem with him on solo que is that he gets countered hardcore and can be camped due to his lack of escapes. I prefer to play him a tanky-cdr bruiser.
He is extremely strong in games where you have a team that can capitalize on his speed buffs and amazing initiation/catches with his ult.
You can almost always build a good defensive item that gives you more innate sustain/offensive power. It's amazing that his Q does % of max health. Resistances stack extremely well on him because his Q and auto attack heals become worth more ( effective HP due to resists ).
Building a tanky dps wick works extremely well too. Although manamura is an extreme investment with little defensive payoff, it makes his ult do extreme amounts of damage. 5 procs of manamura and around 450 damage makes your ult do ~1K damage. Pair this with a few auto attacks, few q's, and ignite and you can 1v1 almost any champ. Manamura goes well with frozenheart/Iceborn gaunts/banshees veil.