I'll give you a run down of my experience. I will preface by saying I have not used PowerBot for OSRS(has been great for RS3), EpicBot, or HydraBot.
TriBot regular client and scripting -
Pros: Good antiban features built-in, client interface is on-point, and many scripts available.
Cons: Still experienced hefty number of bans, however this is only while using their regular client. You have to be VIP for botting past a few hours every so often.
TriBot looking-glass -
Pros: Same scripts available, same amazing antiban, no bans to date.
Cons: Requires more computer resources, still in beta. However, things are looking up still. You have to be VIP+ to use.
OSBot -
Pros: Client is pretty awesome especially the tabs, already has a pretty well developed reflection client have noticed less bans, is "free" for unlimited amount of time botting with one account.
Cons: Need VIP for some features, didn't use it long enough to find out too much.
TopBot client(only used reflection only) -
Pros: No bans yet, free to bot however much you want, good API and scripting community.
Cons: Not as popular so there might be scripts lacking in some departments, pay to use some features(i.e. proxies/breaks).
Simba -
Pros: Completely free, amazing scripting community, great support for color botting and reflection botting, have not received a ban yet.
Cons: If you are not a script writer, it can be very difficult to make good use of Simba(however, there are still amazing scripts for some things), no robust client, definitely not as easy to use as other bots out there.
My rankings:
1. Simba/TopBot tied, Simba being completely free but can be unwelcoming due to it's more complex nature, and TopBot for being mostly free but very welcoming.
2. OSBot. Overall decent in most aspects, yet fails to be outstanding in any particular aspect at the moment. Yet, it's free for the most part and
3. TriBot Looking Glass, TriBot has great script availability and premade antiban features scripters can use, now with reflection ban rate(for me) has gone way down. Still in beta and quite pricey for main features. Might be one of the best once Looking Glass is further developed and is more available to other paying users.