In terms of rsbuddy compared to powerbot where safety is concerned;
Every script which is submitted to rsbuddy is checked before it is placed in the repo, so there will not be any malacious code.
Whereas for powerbot, anyone can post their code and it is not checked.. unless spotted by someone on the forum as you have to compile your own scripts.
I'd say generally, in my opinion of using both I would stick with RsBuddy as the quality of the scripts is often better and the client also, in my opinion is better.
Just have a look through the feedback before you use the bot so you can get an idea of how flawless/buggy it is.
yea rsbuddy is way safer than pb. no1 has ever been hacked on rsbuddy as with pb theres an average of 5ppl a day. most scripts are flawless. its hard to make a flawless script now bc rs is constantly updating so the scripters have to rewrite the scripts
they all work from the ones i have tried, the only problem i have seen is some are rather slow and look like a bot, rsbuddy is a safe botting program, i have used it for the past months and it works really well