Jagex is more aware of rule-breaking in RuneScape 2, so there is less chance of you getting banned on RSC, but to be safe, don't use rubbish bots that clicks on the same place(s) all the time.
Does Jagex even tend RSC at ALL. It seems that I can do virtually anything without being even muted. Don't want to try my chances, but thats what it seems.
Just bot where a mod is not likely to walk by, they like to sit around in a bank and itch their nut on classic, quite useless players. The mod's ask more questions than I do.