http://runedream.org/
http://www.epicbot.com/
http://villavu.com/forum/
http://www.robotzindisguise.com/forum/
Runedream has potential, but their forums had a major setback and they probably won't have a downloadable client for a week or so. It's definitely worth checking out, but at the moment you can probably only find the old client uploaded by someone else, which may be a bit 'iffy' to download. There are not too many scripts on the official forum, but with some nifty google or pastebin search, you could probably find some decent scripts to use.
Such as:
https://www.google.com/search?q=imp...=681&bav=on.2,or.r_gc.r_pw.r_qf.,cf.osb&cad=b
Epicbot is probably the best at the moment, but there is a lot of speculation about their legitimacy. I've had great results with their Runecrafter running for at least 6 hours straight -- just last night, and I've heard good things about their combat script. I would definitely recommend Epicbot.
Villavu is Simba, which you've probably heard of. I personally haven't had great luck with their scripts, but some people really like the bot. I've managed to run some Simba Herblore scripts for hours on end. I've heard decent things about their combat scripts, but haven't tested any. It's probably more difficult to set up than the others, so if you're not too computer-savvy, it's probably not the best option.
Robotz in Disguise is quite expensive (but there is a 6 hour free trial). The bot takes control of your mouse, so you can't do anything else while botting. They have a free Power Miner and Oak Larder Maker (construction) bot.
Powerbot is no longer functional, but they claim to be up and running soon -- but, they've been saying that since November 2011.
Rsbots.net looks like it's down for good.
Rsbuddy.com is no longer a botting site.