There are currently 99% less bots at the green dragons, lvl 20 wilderness. So either, it's something to do with the log in issues created by the Crucible update, or they have already been releasing sneaky patches to combat the bots. I can see the bot patches, becoming a weekly update.
Yes, Bots will never be removed 100% for more than 24 hours, as there is too much money in it for the makers and users of botting software. With all this Anti-virus/Firewall software out there, you don't see the Hackers and Virus Creators shutting down shop!
Colour bots can be disrupted, quite easily actually.. with these updates, all they need is a few items' colour's, to be changed every day, week, month... and voila, they have a disruptive system; the bots will have to be updated as frequently as Jagex's colours. Just think if they cycled the colours every hour. Bots would become a very manual operation, instead of a Computer Farm running 24/7.
Anyway, I don't think there will be many more Nukes, Just a few fire crackers thrown in the mix... It's just not worth Jagex spending the man hours on massive patches, when even the small patches have the potential to have the same affect.