Color bots are generally the safer route to take, but if a bot is not made very well, you'll still end up banned. Even high quality scripts may lead to a ban because Jagex is just taking things up a notch. While they eliminate a huge risk (by not interacting with Jagex's game code) by screenscraping instead of injection/reflection, Jagex's detection systems involve other tools, like analysis of mouse movements, inhuman behavior, and many more things.
Ultimately, with color bots, your risk really lies with how good the developer is.