Merlin's Crystal is need to use Excalibur in the Holy Grail, the boss is really easy to kill...
Witches house is easy quest, idk what debuff you talking about...
Also Mountain Daughter and The Grand Tree requires agilitiy, you will lost time leveling that...
Lost City requires, that's more time of boring leveling...
In fact, to complete my list of quest you only need 60/60/60 Melee and some food...