https://community.skype.com/t5/Windows-archive/Settings-are-reset-at-startup/td-p/4123904 said:
Quit Skype or use Windows Task Manager to kill any Skype.exe process. Go to Windows Start and in the Search/Run box type %appdata% and then press Enter or click the OK button. The Windows File Explorer will pop up. There locate a folder named “Skype”. Rename this folder to something different, e.g. Skype_old.
Next go to Windows Start and in the Search/Run box type %temp%\skype and then press Enter or click the OK button. Delete the DbTemp folder.
Restart Skype.
If needed, you will still be able to re-establish your call and chat history. All data is still saved in the Skype_old folder.
