Well I'm glad you say you are getting Defence up soon, I would raise:
Attack
Strength
Defence
(HP comes with those 3 so I won't bother saying that)
Magic
Prayer
Herblaw
Summoning
Raise the above while getting quests in, this will also require you to raise other stats so you meet quest requirements.
Once you have a fair bit of quests under your belt (maybe 270-290 quest points, preferably with the big quests done like While Guthix Sleeps, etc. so you get big xp and item rewards), start bossing.
If your stats are still fairly low at the end of your questing for rewards/XP, start bossing at Bandos GWD and Zammy GWD. Then later on move up to things like Sara GWD and Corporal Beast. I would recommend not doing Corp until you are maxed, though.
Explanations on why to raise the stats mentioned:
Att/Str/Def: obvious reasons
Magic: So you have greater Magic Defence
Prayer: So you can use better Prayers, and eventually better Curses. Also so your prayer lasts longer, and you get more points from Prayer Potions
Herblaw: So you can make your own potions (not such of a big deal until you get into high level/elite teams where you will want to use Extremes/Overloads/Spec restore pots)
Summoning: Summoning can be expensive depending how you get your charms (Slayer should give you enough drops to make Summoning free), but it benefits you in absolutely everything you do in RuneScape.
Tl;dr Raise combat, get essential and rewarding quests done, then go bossing.