Great to see you around sythe again, Aonor. I've been spending the past weeks at Runespan. I've found a couple methods which work very well.
You could either locate a central island, where you will gather your essence from esshounds, wraiths etc. And sipher nodes which happen to spawn on your island.
Or, you could find a central island, to gather essence and runes. Once you have gained sufficient amounts of runes, you can use the platforms to move to surrounding islands where nodes spawn more often.
The first method is more afk-friendly.