Okay well if you use and RSbot or its client you will have noticed they have gone away with "SAFE MODE" so anyone figured out how to get the bot working and it to stop flashing like a madman?
Do Jagex still have that animated loading screen? If so, turn it off in settings.
Put it in safe mode and using the lowest quality settings possible.
There's no safe mode.
Put it to software mode and set it to min/med.

