Fairly sure I've seen reputable YT users using it and explicitly stating that you won't be banned for using the program. From memory I also remember seeing a J-Mod statement on the matter which indicated the features of Orion were safe to use, however they aren't responsible for malicious files on the client etc. I believe the owner of the client is a P-Mod named "Skiller", correct me if I'm wrong however.
Just thought I'd put it out there that the creators of Orion are actually very close friends of Mod Jacmob's. Rogie and a few others helped him and are a part of the old RsBuddy community who now work with jacmob on projects and such like orion.